Maryam Vasefi


Assistant Professor

Department of Biology

Office: 205-7 Hayes Biology Building
Phone: 409-880-7090


2014 Ph.D. in Pharmacology, School of Pharmacy, University of Waterloo, Ontario, Canada

Courses Taught:
Medical Neuroscience (BIOL 5401, 4401)
Molecular Genetics (BIOL 5401, 4401)
Anatomy and Physiology (BIOL 2401)
Microbiology (BIOL 2420)
Biology 1 & 2 (BIOL 1306, 1106, 1307, 1107)



Research Interests:
Drug Design
Signal Transduction

Research Group:
Vasefi2 - Constance
Stephanie Constance 
Stephanie served as an active duty service member of the United States Army from September 2004 to November 2013. Currently, she is interested in cell and molecular biology and plans on pursuing a career in this study while under the guidance of Dr. Maryam Vasefi. 
Amanda Warner
Amanda Warner
Amanda is a Junior Biology major and Chemistry minor with a concentration in pre-med. She has a passion for learning and serving her community. She has been a member of the American Medical Student Association, Reformed University Fellowship, American Society for Biochemistry and Molecular Biology, and Trinity University Players. She was recently named a 2018 Presidential Summer Fellow and will conduct research in the Department of Clinical Neurosciences at the Cambridge Centre for Brain Repair on Parkinson’s disease. She has been working with Dr. Vasefi on the use of polyphenols in the prevention and treatment for Alzheimer’s disease. This research was presented at the 5th Annual Texas STEM Conference and a research grant was awarded to continue this work. 
Dhillon Gurpartap
Dhillon Gurpartap
Dhillon is a recent graduate of Baylor University, having received a Bachelor of Science degree in Biology. Currently, he is conducting research with Dr. Vasefi on molecular pathways that result in symptoms of Alzheimer’s disease and how different drugs affect them. Additionally, he is also researching preventative measures that can be taken to postpone the onset of, and reduce cognitive decline from, neurodegenerative diseases. In the near future, he plans on pursuing a career in Optometry. 
Bianca Rangel
Bianca Rangel
Bianca was born and raised in Southeast Texas where I am currently a junior student pursuing a degree in Biology with a chemistry minor. I have been working as a pharmacy technician for the past three years and plan on pursuing a career in the medical field. I have a passion for learning and understanding the pathophysiology of many diseases. I am now working as a Student Research Assistant under the instruction of Dr. Vasefi discovering the measures in the prevention of Alzheimer’s disease such as physical and cognitive exercise. 
Jorge Oseguera
Jorge Oseguera
Jorge is a senior pursuing a degree in psychology with a chemistry minor. While being a full-time student Jorge also works full-time running a business. He is passionate about neuroscience, curious to find answers explaining human behavior. Jorge has directed two of his own experiments analyzing perceptions of racially ambiguous individuals and how interactions and environmental cues affect those perceptions. He joined Dr. Vasefi’s research team to learn more about neuroscience from a biological aspect. 
Mackenzie Hudson
Mackenzie Hudson
Mackenzie is a junior Psychology student who is pursuing a minor in Biology. After graduation, she plans to seek her PhD in clinical psychology. She is currently working with Dr. Vasefi on research involving factors that may delay the onset of Alzheimers disease or even help people already suffering from this illness.  
Hamzah Abedelwahab
Hamzah Abedelwahab
Hamzah is a senior pursing a degree in Biology and a minor in Chemistry. With his degree, he wishes to acquire a position within the medical field. He enjoys physical fitness, the outdoors, and cooking. Conducting research with Dr. Vasefi has allowed him to discover not only the pathogenesis/preventative measures behind Alzheimer’s disease, but the multitude of histopathological changes and the pathophysiology of said changes in Alzheimer’s disease. 
Vasefi3 - Ali
Roshney Ali 
Roshney is a junior student who is pursuing a degree in Biology. She actively served for 5 years as the Head of Public Speaking and Rituals at her church from January 2012 to November 2016. Roshney holds position at her church as the Marketing Lead, Disaster Management Assistant Lead, and the Head of Operations for weekday school. She enjoys getting involved on campus and has a passion for learning. She plans on pursuing a career in the dental field and is currently being mentored by Dr. Vasefi for her research. Roshney loves to spend time with her family and is motivated to help others. 
Emily Maccall
Emily Maccall
Emily is a junior undergraduate student at Lamar University who is currently acquiring a degree in Biology. She is an active member of a number of on-campus organization, having served as the Vice President of the Honors Student Association and as a member of the Lamar University Ambassadors. She also enjoys spending her free time volunteering at Beaumont's Shorkey Center and taking care of her pets. Emily plans to pursue a career in the medical field, with the dream of one day becoming a physician.
Former Lab Members:
Neda Fallah, Research Assistant
Shreya Vakil, TALH student  

Accepting Master Students? YESAccepting undergraduate Students? YESIf you are interested, please do not hesitate to contact Dr. Vasefi. 

Selected Publications:

Alison Hamilton, Maryam Vasefi, Cheryl Vander Tuin, Stephan Ferguson, “Chronic pharmacological mGluR5 inhibition ameliorates cognitive impairment and pathogenesis in an Alzheimer's disease mouse model” Cell Receptor, 2016

Wesseem Osman, Tarek Mohamed, Victor Munsing Sit, Maryam S. Vasefi, Michael Beazely, Praveen P.N. Rao, “Structure-activity relationship studies of benzyl-, phenethyl-, and pyridyl-substituted tetrahydroacridin-9-amines as multitargeting agents to treat Alzheimer’s disease” Chemical Biology & Drug Design, 2016

Atefeh S. Zara, Maryam S. Vasefi, Tiemin Huang, John G. Mielke “Capillary isoelectric focusing with whole column UV detection (CIEF-UV-WCID) to characterize human salivary α-amylase”, Clinical Biochemistry, 2015

Ryan M. Bradley · Emily B. Mardian · Phillip M. Marvyn · Maryam S. Vasefi · Michael A. “Beazely · John G. Mielke · Robin E. Duncan. Data on acylglycerophosphate acyltransferase 4 (AGPAT4) during murine embryogenesis and in embryo-derived cultured primary neurons and glia” Data in brief, 2015

Jeff Kruk, Maryam S. Vasefi, Nyasha Gondora, Nawaz Ahmed, Jhon J. Heikkila1, and Michael A. Beazely. “Fluoxetine-induced transactivation of the platelet-derived growth factor type β via serotonin receptors reveals a heterologous desensitization mechanism” Molecular and Cellular Neuroscience, 2015

Ansula Samarajeewa, Lollita Goldman, Maryam S. Vasefi, Nawas Ahmed, Nyasha Gondora, Chandni Khanderia, John Mielke, Michael Beazely “5-HT7 receptors activation promotes an increase in TrkB receptor expression and phosphorylation” Frontiers in Behavioral Neuroscience, 2014

Jeff Kruk, Maryam S. Vasefi, J. J. Heikkila1, and M. A. Beazely. “Reactive Oxygen Species Are Required for 5-HT-Induced Transactivation of Neuronal Platelet-Derived Growth Factor and TrkB Receptors but Not for ERK1/2 Activation” PlosOne, 2013

Vasefi MS, Yang K, Li J, Kruk JS, Heikkila JJ, Jackson MF, Macdonald JF, Beazely MA “Acute 5-HT7 receptor activation increases NMDA-evoked currents and differentially alters NMDA receptor subunit phosphorylation and trafficking in hippocampal neurons” Molecular Brain, 2013

Maryam S. Vasefi, Jeff Kruk, John J. Heikkila1, and Michael A. Beazely, “5-HT7 receptor-mediated neuroprotection against NMDA–induced excitotoxicity is PDGFß receptor-dependent” Journal of Neurochemistry, 2013

Jeff Kruk, Maryam S. Vasefi, Liu Hu, J. Heikkila, Michael A. Beazely, “5-HT1A receptors transactivate the platelet-derived growth factor receptor type beta in neuronal cells”, Journal of Cell Signaling, 2013

Tarek Mohamed; Jacky Yeung; Maryam S Vasefi; Michael A, Beazely; Praveen Rao, Development and Evaluation of Multifunctional Agents for Potential Treatment of Alzheimer's Disease: Application to a Pyrimidine-2,4-Diamine Template, Bioorganic & Medicinal Chemistry Letters, 2012

Maryam S. Vasefi, Jeff Kruk, Liu Hu, Michael A. Beazely, John J. Heikkila, “Activation of 5-HT7 receptors increases neuronal platelet-derived growth factor ß receptor expression “, Neuroscience letter, 2012